Sildenafil is a potent and selective inhibitor of cGMP-distinct phosphodiesterase form 5 (PDE5), that is to blame for degradation of cGMP inside the corpus cavernosum. The molecular framework of sildenafil is comparable to that of cGMP and functions as a competitive binding agent of PDE5 while in the corpus cavernosum, causing more cGMP and improveā€¦ Read More